Senior Director, Translational Research & Biomarkers

@ Attovia Therapeutics
Attovia Therapeuticsattoviatherapeutics.com

Senior Director, Translational Research & Biomarkers

Posted 1 month ago

This job is still taking applications, but it's been up a while.

About the job

Attovia develops biotherapeutics for immune diseases using innovative biologics. The Senior Director leads translational strategies, biomarker development, clinical integration, and regulatory efforts. Located in San Carlos, CA.

Requirements

  • 10+ years biopharma experience
  • Leadership in biomarker projects
  • Deep knowledge of platform tech
  • Experience with regulatory filings
  • Team management skills

Qualifications

  • PhD or MD in biology or related
  • Proven industry track record
  • Expertise in NGS, IHC, proteomics
  • Strategic and leadership skills

Full job description

We are looking for a strategic and hands-on leader to bridge the gap between early discovery and our patients.  As the Senior Director of Translational Research & Biomarkers, you will design and execute the translational strategies to support the development of our clinical portfolio.  You’ll lead efforts developing and identifying the biomarkers that help identify how to select our patients and to demonstrate that our molecules impact the desired target biology.


Key Responsibilities

  • Strategic Leadership: Develop and lead the overarching translational medicine strategy for the entire pipeline, from lead optimization to Phase II/III.
  • Biomarker Discovery: Oversee the identification, development, and validation of pharmacodynamic, predictive, and prognostic biomarkers.
  • Clinical Integration: Collaborate with Clinical Development to integrate biomarker assays into clinical protocols and ensure high-quality data collection and analysis.
  • Cross-Functional Partnership: Act as the primary link between Discovery Research, Clinical, and Regulatory Affairs to ensure seamless program transitions.
  • External Innovation: Manage relationships with CROs, academic collaborators, and potential diagnostic partners for assay development and companion diagnostic (CDx) strategies.
  • Regulatory Representation: Lead the translational/biomarker sections of regulatory filings (IND, CTA, BLA/NDA) and represent the company in meetings with health authorities (FDA/EMA).

    • Qualifications

  • Education: PhD or MD in Biology, Pharmacology, Oncology, Immunology, or a related field.
  • Experience: 10+ years in the biopharma industry, with a proven track record of moving programs from bench to bedside.
  • Technical Expertise: Deep knowledge of diverse platform technologies (e.g., NGS, IHC, flow cytometry, proteomics, liquid biopsy).
  • Strategic Mindset: Experience developing validated lab tests/Cdx and a strong understanding of global regulatory requirements for biomarkers.
  • Leadership: A history of managing high-performing teams and influencing stakeholders in a fast-paced, matrixed environment.

    • About Attovia

    Attovia is creating a pipeline of biotherapeutics with initial focus immune-mediated disease. The company leverages Attobody™, a novel biologics platform, to generate small format biparatopic binders that expand the addressable target universe across disease areas and can offer stronger efficacy, faster speed to response, and an improved safety profile than traditional approaches. We are currently progressing multiple programs across immune-mediated disease indications.

    Our culture is centered around five core pillars:

    • Integrity
    • Learning & Growth
    • Drive for Excellence
    • Innovation
    • Teamwork & Collaboration

      • We take pride in fostering a strong team and dynamic work environment, and we are seeking individuals who align with our values and contribute to a positive and impactful workplace.  

      Attovia is located in San Carlos, CA.

      Attovia is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. 

      Learn more about Attovia: www.attovia.com


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